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Non-Surgical Treatments · Non-surgical

Salmon DNA

A polynucleotide (salmon DNA) treatment designed to support skin renewal.

Medical content: Op. Dr. Alperen Tekin, Specialist in Plastic, Reconstructive and Aesthetic Surgery · Last updated:

  • FEBOPRAS
  • TPRECD member
  • Suadiye, Kadıköy
Salmon DNA

Salmon DNA: Natural Support for Skin Renewal

Salmon DNA treatment is the application of purified polynucleotides derived from salmon into the skin with fine needles. The aim is to support the skin's moisture retention, elasticity and overall quality. Your treatment plan is determined during your consultation, based on your skin's needs.

What is Salmon DNA (Polynucleotide)?

Polynucleotides are highly biocompatible ingredients; in salmon DNA treatment they are used to support the skin's renewal process. Unlike fillers, the goal is not to add volume but to support the skin's own quality. It is usually planned as a course of sessions at set intervals.

In Which Areas Is It Applied?

Salmon DNA treatment is most often planned for the following areas:

  • Face: For overall skin quality and hydration support.
  • Around the Eyes: For fine lines and a tired appearance.
  • Neck and Décolleté: To support loss of elasticity.
  • Backs of the Hands: To support skin quality.

How Is Salmon DNA Applied?

  • Consultation and Assessment: Your skin's needs are identified and a course plan is created.
  • Preparation: A topical numbing cream may be applied for comfort.
  • Application: The product is applied to the skin with fine needles; the procedure usually takes 20-30 minutes.
  • Follow-up: Session intervals and the full course are personalized during your consultation.

Who Is It Suitable For?

  • People with skin dryness, loss of elasticity or fine lines.
  • Individuals with dull, tired-looking skin.
  • Those with sun damage or smoking-related loss of skin quality.
  • Those seeking natural-looking, non-surgical support.

After Salmon DNA Treatment

You can usually return to daily life on the same day:

  • Mild redness or bumps may occur at the injection points; they usually subside within a few hours.
  • Make-up is not recommended on the day of the procedure.
  • Avoid sauna, swimming pools and intense exercise for the first 24 hours.
  • Regular use of sunscreen is recommended.

Advantages of Salmon DNA Treatment

  • No surgical intervention required.
  • Aims to support the skin's own quality; a natural look is the goal.
  • Can be combined with mesotherapy and other treatments.
  • Return to social life is usually quick.

Risks and Side Effects

When performed by an experienced physician, salmon DNA treatment is generally well tolerated; temporary side effects may rarely occur:

  • Temporary redness, tenderness or bruising.
  • Small bumps (usually subside within a few hours).
  • Rarely, an allergic reaction; suitability is reviewed together during your consultation.

How It Differs From Filler and Mesotherapy

Non-surgical treatments are often grouped together, but the three address different problems.

TreatmentTargetAdds volume?
Salmon DNA (polynucleotide)Supporting tissue renewalNo
MesotherapySupporting skin qualityNo
Dermal fillerAdding volume at a pointYes

The practical distinction: if there is hollowing, filler is considered; if tissue quality is the target, salmon DNA or mesotherapy comes into play. Where there is sagging, none of them is sufficient and surgical assessment is required.

These treatments need not be alternatives to one another; addressing different goals, they can sit in the same plan. See mesotherapy and dermal fillers.

How Many Sessions, and How Long Does It Last?

This is planned as a programme rather than a single session, because the effect is cumulative: the response strengthens as the tissue stimulus is repeated.

The general approach is a series of initial sessions at set intervals, followed by less frequent maintenance sessions to hold the level achieved. Session count and interval depend on the target area, skin condition and individual response.

To be clear about expectations: the result is not visible after the first session; change is gradual, and most people first notice it in how the skin feels and in its luminosity. It is not a permanent treatment — because ageing and environmental effects continue, the level achieved regresses without maintenance.

Treat claims of permanent results, or of marked change in a single session, with caution.

Who Is Not Suitable?

  • Not used during pregnancy or breastfeeding.
  • Not used in people with a known allergy to fish or seafood. Because of the origin of the material, this is specifically asked about and must be mentioned at consultation.
  • If there is active skin infection, an eczema flare or an open wound in the treatment area, the session is postponed.
  • In people with a bleeding or clotting disorder, or taking blood thinners, planning is made with medical input.
  • Where there is uncontrolled systemic illness, that condition is stabilised first.
  • People with an autoimmune condition or receiving treatment affecting the immune system require separate assessment.
  • Not the right method for anyone whose goal is to correct sagging or gain significant volume.

This is a medical procedure and is not appropriate in non-medical settings such as beauty salons.

Salmon DNA Prices

Salmon DNA prices vary depending on the treatment area and the number of sessions planned. Clear information is shared after your consultation.

You can write to us on WhatsApp with your questions; we reply the same day.

Your treatment journey

From your first message to full recovery

Every step is planned with you, and you always know who to reach.

  1. 01

    First Contact

    Message us on WhatsApp — we listen and answer your questions the same day.

  2. 02

    Consultation & Planning

    A personalised plan based on your expectations and examination findings.

  3. 03

    Surgery

    Your personalised procedure is performed comfortably under appropriate anaesthesia.

  4. 04

    Recovery & Follow-up

    We stay with you through regular check-ups at every step of recovery.

Op. Dr. Alperen Tekin

Your surgeon · Specialist since 2019

Op. Dr. Alperen Tekin

Specialist in Plastic, Reconstructive and Aesthetic Surgery · FEBOPRAS

He graduated from Istanbul University Cerrahpaşa Faculty of Medicine and completed his specialty training at Gazi University, one of Turkey's long-established plastic surgery departments. His specialty thesis on breast implants and radiotherapy received an award at the 41st National Plastic Surgery Congress, and he holds the European Board (EBOPRAS) Fellowship.

  • 2012Cerrahpaşa Medicine
  • 92.Specialty exam rank
  • 2019Specialist, Gazi Univ.
  • 2021EBOPRAS Fellow
Read the CV

Frequently asked questions

Questions about Salmon DNA

Each answer is general information; your situation is assessed at the consultation.

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Am I a suitable candidate for salmon DNA?

Suitability is assessed together based on your skin's needs, your expectations and the examination findings.

How many sessions are needed?

It is usually planned as a course; the number and spacing of sessions are personalized during your consultation.

When can I return to social life?

Usually on the same day; injection marks subside quickly.

How much does salmon DNA cost?

The price is personalized based on the area and the course plan; clear information is shared after your consultation. You can write to us on WhatsApp with your first questions.

Appointment

Your personal plan starts with a consultation

We decide together which approach suits you, after listening to your expectations and examining you in person.

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